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Remail was written to sidestep the hard-to-solve problem of sending encrypted mail to multiple people, some of whom may prefer to use GnuPG, some PGP from Symantec, while others use S/MIME from coroprate-issued CAs that are not in universal CA trust stores.
Remail accepts both S/MIME and PGP-encrypted email sent to a single address, decrypts it on the back-end, and then recrypts to individual list subscribers using whichever is their preferred scheme for email encryption.